UPMC Physician Resources

Archives for Transplantation

UPMC 2016 Lung Transplant Conference Wet Lab

Jonathan D’Cunha, MD, PhD, FACS, discusses the Heart/Lung Procurement Wet Lab component of the 2016 Lung Transplant Conference. The conference will be held in Pittsburgh on Thursday, Nov. 10 and Friday, Nov.11, 2016.

 

To learn more and register for the event, visit the event website.

UPMC Lung Transplant Conference 2016

UPMC is hosting its first ever annual lung transplant conference on Thursday, Nov. 10 and Friday, Nov. 11, 2016. Jonathan D’Cunha, MD, PhD, FACS, and Matthew Morrell, MD, discuss highlights of the 2016 Lung Transplant Conference:

 

To learn more and register for the event, visit the event website.

UPMC Launches New Series: Video Rounds

UPMC has launched Video Rounds. Video Rounds is a series of informative and educational short videos, created for physicians and covering a variety of medical and surgical disciplines. New topics are always being added and include:

Endocrinology: Inpatient Diabetes Management
Gastroenterology: Developing a Center of Excellence for Pancreatic Disease Treatment
Geriatrics: Clinical Implications of Depression in the Geriatric Population
Gynecology: Advances in Prenatal Diagnosis of Genetic Conditions
Heart and Vascular: The Role of ECMO and VADs in Treating Acute Heart Failure
Neurosurgery: Microvascular Decompression in the Treatment of Cranial Nerve Disorders
Oncology: Using Big Data and Genomic Research to Develop Personalized Medicine
Ophthalmology: New Imaging Technology for Retinal Diseases
Orthopaedic Surgery: Diagnosis and Management of Diabetic Foot Infections
Pediatrics: Multidisciplinary Approach to Tongue-Based Airway Obstruction
Pulmonology: Endobronchial Coils to Treat Chronic Obstructive Pulmonary Disease
Rehabilitation: Early Mobility and Rehabilitation in the ICU: A Paradigm Shift
Rheumatology: A Primer of Myositis
Psychiatry: Considerations for Treating Women with Substance Use Disorder
Urology:Partial Nephrectomy: The Preferred Option for Treating Localized Kidney Cancer

The full video rounds library can be found here.

Analysis of Incidence and Survival After Liver Transplantation for Hepatoblastoma

In a recent study, researchers found that liver transplantations to treat hepatoblastoma are increasing, along with the overall incidence rate of the disease across the U.S. Favorable histology and early referral to surgery are increasingly linked to a greater chance of survival after resection, and could also determine improved post-transplantation outcomes.

Rakesh Sindhi, MD, director, Pediatric Transplant Research, Children’s Hospital of Pittsburgh of UPMC, talks about the results and implications of the study, which was published in the February 2013 issue of Surgery.


 

Management and Outcome of BK Viremia in Renal Transplant Recipients: A Prospective Single-Center Study

BK viremia can lead to nephritis, which can progress to irreversible kidney transplant failure. This prospective study provides management and outcome of BK viremia in renal transplant recipients.

The study concludes that reduction in immunosuppression alone resulted in the successful resolution of viremia with preservation of renal function and prevention of clinical BKV nephritis and graft loss.

“Management and Outcome of BK Viremia in Renal Transplant Recipients: A Prospective Single-Center Study” was published in the October 27 issue of Transplantation. Sundaram Hariharan, MD, medical director, UPMC Kidney and Pancreas Transplantation Program provides some additional information about it in his video blog.

Optical Coherence Tomography for Detection of Cardiac Allograft Vasculopathy (OCTCAV Study)

Sameer Khandhar, MD, presented “Optical Coherence Tomography for Detection of Cardiac Allograft Vasculopathy (OCTCAV Study),” at the International Society for Heart and Lung Transplantation’s 32nd Annual Meeting and Scientific Sessions in Prague, Czech Republic. He discussed the results of this study which explored optical coherence tomography for earlier detection and more accurate characterization of coronary allograft vasculopathy.

http://www.sciencedirect.com/science/article/pii/S1053249812002823

Hear more about this work from Dr. Khandhar:

Thyroxin Administration during Donor Management Is Associated with Improved Graft Survival in Adult Liver Transplant Recipients

At the upcoming American Transplant Congress, Christopher Hughes, MD, will present a session entitled, Organ Preservation (Liver) and Liver Allocation, where he will discuss a recent study “Thyroxin Administration during Donor Management Is Associated with Improved Graft Survival in Adult Liver Transplant Recipients”.

Hormonal treatment with thyroxin (T4) has been suggested to protect the viability of donated organs and to improve the utilization of organs from deceased donors. However, data as to whether this approach improves graft survival is lacking. The aim of this study was to evaluate the impact of T4 use on graft survival after orthotropic liver transplantation (OLT) in adults.

We retrospectively reviewed database records of 1,231 adult patients who underwent OLT between January 2003 and September 2011. Donor demographics, vasopressor drug administration, use of T4 infusion, and cold (CIT) and warm (WIT) ischemia times were included in the analysis. Kaplan-Meier method with long rank test was used to determine the association of potential variables with graft survival. Cox-proportional hazards regression was used for multivariate analysis.

If you are attending the 2012 American Transplant Congress in Boston, consider attending the Organ Preservation (Liver) and Liver Allocation session on June 5, 2:15 p.m., in room 312.

Authors on the study include: Christopher Hughes, Mehmet Can, Roberto Lopez, Mark Sturdevant, Abhinav Humar. Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA

Determinants of Early Outcome in Pediatric Liver Transplantation

At the upcoming American Transplant Congress, George Mazariegos, MD, will present a session entitled, Pediatric Liver Transplantation, where he will discuss a recent study “Determinants of Early Outcome in Pediatric Liver Transplantation.”  

Although overall outcomes after pediatric transplantation (Tx) are very good, early death or graft loss contributes a significant proportion of overall mortality or retransplantation. The Studies in Pediatric Liver Transplantation (SPLIT) database was analyzed to determine factors predictive of 7 and 30 day mortality or graft loss. Multivariate models using factors available at the completion of Tx (baseline model) were compared to a model including 30 day chemistries and complication events (cumulative model).

Hear more about this presentation:

If you are attending the 2012 American Transplant Congress in Boston, consider attending the Pediatric Liver Transplantation session on June 5, at 2:39 p.m., in room 310.

Authors on the study include: G. V. Mazariegos, R. Anand, W. Yin, S. McDiarmid, J. M. Millis, J. Magee, B. Kelly, J. Bucuvalas, SPLIT Research Group. Children’s Hospital of Pittsburgh of UPMC; The EMMES Corporation; UCLA Children’s Health Center; Univ. of Chicago Medical Center; Univ. of Michigan Medical Center; Vanderbilt Univ. Medical Center; Cincinnati Children’s Hospital Medical Center

Islet Autotransplantation (IATx) at UPMC

At the upcoming American Transplant Congress, Martin Wijkstrom, MD, will present a session entitled, Total Pancreatectomy/Islet Autotransplantation, where he will discuss a recent study “Islet Autotransplantation (IATx) at UPMC.”  

IATx is a rescue procedure in patients undergoing total pancreatectomy (TP) for the treatment of debilitating pain from pancreatitis. The aim of the study was to monitor those patients who had undergone IATx and the outcomes from islet processing and clinical results.

Hear more about this presentation:

If you are attending the 2012 American Transplant Congress in Boston, consider attending the Total Pancreatectomy/Islet Autotransplantation session on June 4, 3:15 p.m., in room 310.

Authors on the study include: Martin Wijkstrom, Rita Bottino, Andres Gelrud, Adam Slivka, Frederico Toledo, Amy Singh, Massimo Trucco, Kyle Soltys, A. James Moser, Abhinav Humar. Department of Surgery, University of Pittsburgh, Pittsburgh, PA; Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA; Department of Medicine, University of Pittsburgh, Pittsburgh, PA

7th International Pediatric Intestinal Failure and Rehabilitation Symposium

Children’s Hospital of Pittsburgh of UPMC is proud to be a sponsor of the 7th International Pediatric Intestinal Failure and Rehabilitation Symposium, on September 6-8, 2012. 

Abstracts deadline:  July 1, 2012
Click here for submission guidelines and online conference registration.

George Mazariegos, MD, director, Pediatric Transplantation at Children’s Hospital of Pittsburgh of UPMC, discusses the structure of the three-day conference, as well as presentation and discussion topics:

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