The UPMC Heart and Vascular Institute will be well-represented at the American College of Cardiology (ACC) 65th Annual Scientific Session in Chicago. Faculty research was featured in both oral and poster presentations throughout the conference, including:

Saturday, April 2

ACC.i2 Aortic and Mitral Disease, AMI: Innovation, Outcomes, and Practice

Early Recovery of Left Ventricular Ejection Fraction After CoreValve TAVR: Findings From the CoreValve Pivotal Trials

Presented by: Harold Dauerman, Michael Reardon, Jeffrey Popma, Stephen Little, João Cavalcante, David Adams, Neal Kleiman, Jae Oh

ACC.i2 Interventional Cardiology: Complex Patients/Comorbidities

Use of Clopidogrel Versus Prasugrel in Patients Undergoing Percutaneous Coronary Intervention: Factors Influencing Real-World Therapeutic Decision-Making

Presented by: Olga Salianski, Usman Baber, Samantha Sartori, Melissa Aquino, Jaya Chandrasekhar, Annapoorna Kini, Sunil Rao, William Weintraub, Sandra Weiss, Timothy Henry, Samir Kapadia, Kanhaiya Poddar, Anthony DeFranco, J. Muhlestein, Catalin Toma, Mark Effron, Stuart Keller, Brian Baker, Stuart Pocock, Roxana Mehran

ACC.i2 Interventional Cardiology: Translation and Pre-Clinical Research

Low Dose tPA Improves Reperfusion Efficacy of Microvascular Obstruction Using Ultrasound With Microbubbles

Presented by: Akash Goyal, Francois Yu, Mathea G. Tenwalde, Xucai Chen, Flordeliza Villanueva, John Pacella

Sonoreperfusion for Microvascular Obstruction Using Ultrasound and Microbubbles: Role of Nitric Oxide

Presented by: Francois Yu, Xucai Chen, Flordeliza Villanueva, John Pacella

Acute Myocardial Infarction

Incidence, Predictors and Impact of Stroke After Percutaneous Coronary Intervention for Acute Coronary Syndromes: Results From the PROMETHEUS Registry

Presented by: Gennaro Giustino, Usman Baber, Samantha Sartori, Shunsuke Aoi, Melissa Aquino, Jaya Chandrasekhar, William Weintraub, Sunil Rao, Sandra Weiss, Timothy Henry, Samir Kapadia, Kanhaiya Poddar, Anthony DeFranco, J. Muhlestein, Catalin Toma, Mark Effron, Stuart Keller, Brian Baker, Stuart Pocock, Roxana Mehran

Can We Do Better with Atrial Fibrillation Ablation?

Incidence and Predictors of Complications and Phrenic Nerve Injury During Cryoballoon Ablation for Atrial Fibrillation

Presented by: Emily Guhl, Donald Siddoway, Evan Adelstein, Andrew Voigt, Samir Saba, Sandeep Jain

Changing the Treatment of Heart Failure

Tools for Real-Time Patient Management

Presented by: Jeffrey Teuteberg

Heart Failure and Cardiomyopathies: Basic

Cardiac Gene Expression Profile Distinguishes African-American and European-American Heart Failure Profiles

Presented by: Indrani Halder, Victoria Causer, Charles McTiernan, Bonnie Lemster, Ravi Ramani, Sumanth Prabhu, Mark Slaughter, Daniel Dries, George Tseng, Dennis McNamara

Heart Failure and Cardiomyopathies: Medical Therapy

Genomic Score to Target Therapy with a Fixed Dose Combination of Hydralazine and Isosorbide Dinitrate

Presented by: Dennis McNamara, Arthur Feldman, Clyde Yancy, Anne Taylor, Daniel Dries, Karen Hanley-Yanez, Indrani Halder

Joint Symposium of the American Association for Thoracic Surgeons and the American College of Cardiology

Nikaidoh Operation (Video)

Presented by: Victor O. Morell

Lipids, Diabetes Mellitus and Inflammation in Stable Ischemic Heart Disease

Lower Circulating Levels of Tumor Necrosis Factor Related Apoptosis-Inducing Ligand (TRAIL) Are Associated With Increased Sub-Clinical Coronary Atherosclerosis in Smokers

Presented by: Oluremi Ajala, Divay Chandra, Yingze Zhang, Steven Reis, Samir Saba, Frank Sciurba

New Insights into Device Therapy

Left Ventricular Lead Related Complications in Quadripolar Versus Bipoloar Leads

Presented by: Shasank Rijal, Jonathan Wolfe, Andrew Althouse, Rohit Rattan, Sandeep Jain, Samir Saba

Novel Echocardiographic Methods for Evaluating Cardiac Function

Association of Global Longitudinal Strain with Severity of Neurocardiac Injury in Patients with Subarachnoid Hemorrhage

Presented by: Zhi Qi, Masataka Sugahara, Elizabeth A Crago, Yuefang Chang, Theodore F Lagattuta, Khalil Yousef, Robert M Friedlander, Marilyn T Hravnak, John Gorcsan

Novel Prognostic Markers in Pulmonary Vascular Disease

PVR but Not DPG Predicts Cardiac Hospitalizations in Left Heart Disease-Associated Pulmonary Hypertension

Presented by: Rebecca R. Vanderpool, Melissa Saul, Seyed-Mehdi Nouraie, Mark Gladwin, Marc Simon

Nuclear Cardiology in 2015 and 2025: Joint Symposium of the American Society of Nuclear Cardiology and the American College of Cardiology

Cardiomyopathies: Why Nuclear Cardiology Will Not Fail

Presented by: Prem Soman

Pulmonary Hypertension and Pulmonary Thrombo-Embolic Disease I

Correlation of a New Echocardiographic Index of Right Ventricular Remodeling in Pulmonary Hypertension With Invasive Hemodynamics in Rat Model

Presented by: Akiko Goda, Masataka Sugahara, Antonia Delgado-Montero, Bhupendar Tayal, Dmitry Goncharov, Rebecca Vanderpool, Jeffrey Baust, Elena Goncharova, John Gorcsan

Self-Paced Learning Lab: Heart Songs and ECG Practice

Moderated by: John Power

TAVR World – Trials and More of Interest to All

Pacemaker Dependency After Transcatheter Aortic Valve Replacement Is Associated With Reduction in Global Left Ventricular Function

Presented by: Masataka Sugahara, Antonia Delgado-Montero, John Schindler, Thomas Gleason, João Cavalcante, William Katz, Frederick Crock, David Schwartzman, Lisa Henry, Joon Lee, John Gorcsan

Vascular Medicine: Aortic and Peripheral Artery Diseases

Demographic Differences in the Interventional Therapy of Acute Aortic Dissection

Presented by: Uchenna C. Okoro, Ali Khoynezhad, Marek Ehrlich, Mark Peterson, Anil Bhan, Himanshu Patel, Truls Myrmel, Thomas Gleason, Marco Di Eusanio, Lori Conklin, Khaled Abdul-Nour, Nathaniel I. Costin, Daniel Montgomery, Teng Lee, Eric Isselbacher, Christoph A. Nienaber, Eduardo Bossone

Onset of In-Hospital Complications in Acute Type B Aortic Dissections Initially Uncomplicated

Presented by: Arnoud Kamman, Alan Braverman, Eduardo Bossone, Thomas Gleason, Toru Suzuki, Reed Pyeritz, Kevin Harris, Hans-Henning Eckstein, Udo Sechtem, Gilbert Upchurch, Kevin Greason, Daniel Montgomery, Eric Isselbacher, Christoph A. Nienaber, Kim Eagle, Santi Trimarchi

Sunday, April 3

Advances in Echocardiography

An Echocardiographic Risk Score for Prediction of Mortality in Patients with Pulmonary Hypertension

Presented by: Rishin Handa, Srinivas Vunnam, Masataka Sugahara, Akiko Goda, Omar Batal, Michael Mathier, John Gorcsan

Better Diagnosis and Treatment for AF and SVT

Depression Predicts All-Cause 2-Year Mortality in Patients With Atrial Fibrillation and Heart Failure

Presented by: Bruno Lima, Tianxiu Wang, Chung-Chou Chang, Samir Saba, Bruce Rollman

Changing the Treatment of Heart Failure

Tools for Real-Time Patient Management

Presented by: Jeffrey Teuteberg

Clinical and Therapuetic Factors Affecting Outcome After Acute Coronary Syndromes

Predictors of 1 Year Net Adverse Cardiovascular Events (NACE) Among ACS Patients Undergoing PCI With Clopidogrel or Prasugrel: Analysis From the PROMETHEUS Registry

Presented by: Siddharth A. Wayangankar, Usman Baber, Kanhaiya Poddar, Sandra Weiss, Timothy Henry, J. Muhlestein, Brian Baker, Roxana Mehran, Annapoorna Kini, Samantha Sartori, Sunil Rao, William Weintraub, Craig Strauss, Anthony DeFranco, Catalin Toma, Stuart Keller, Mark Effron, Samir Kapadia

Discoveries in Peripartum Cardiomyopathy

Global Longitudinal Strain at Presentation Is Prognostic of Subsequent Left Ventricular Recovery in Patients With Peripartum Cardiomyopathy

Presented by: Masataka Sugahara, Dennis McNamara, Navin Rajagopalan, Joan Briller, Julie Damp, Gretchen Wells, Mark Drazner, Lori Blauwet, Leslie Cooper, John Gorcsan

Emerging Applications in Echocardiography: Part I

Does Echo Equipment Vintage Reflect Commitment to Quality? Assessment by IAC Accreditation Status

Presented by: Saurabh Malhotra, Mary Beth Farrell, William Katz, Prem Soman

Heart Failure and Cardiomyopathies: Transplantation/Stem Cells/Catheter Based Therapies

The Final Results of the IxCell-DCM Trial: Transendocardial Injection of Ixmyelocel-T in Patients With Ischemic Dilated Cardiomyopathy

Presented by: Timothy D. Henry, Arshed Quyyumi, Gary Schaer, R. David Anderson, Catalin Toma, Cara East, David Recker, Ann Remmers, James Goodrich, Amit Patel

Multimodality Imaging in Cardiomyopathy

Fibrosis Imaging in Cardiomyopathy

Presented by: Erik B. Schelbert

Multimodality Imaging in Cardiomyopathy

Pathophysiology of Ischemic Cardiomyopathy: Implications for Diagnosis

Presented by: Prem Soman

Novel Approaches to HFpEF and Other Common Dilemmas

Neurocardiac Injury in Patients with Subarachnoid Hemorrhage is Associated with Regional Left Ventricular Discoordination

Presented by: Zhi Qi, Masataka Sugahara, Elizabeth A Crago, Yuefang Chang, Theodore F Lagattuta, Khalil Yousef, Robert M Friedlander, Marilyn T Hravnak, John Gorcsan

Preventive Cardiology Potpourri

Endothelial Dysfunction and Racial Disparities in Mortality and Adverse Cardiovascular Disease Outcomes

Presented by: Sebhat Erqou, Kevin Kip, Suresh Mulukutla, Aryan Aiyer, Steven Reis

Pulmonary Hypertension and Pulmonary Thromo-embolic Disease II

Echocardiographic Prognostic Markers in Connective Tissue Disease Associated Pulmonary Hypertension Differ from Idiopathic Pulmonary Hypertension

Presented by: Srinivas Vunnam, Rishin Handa, Masataka Sugahara, Akiko Goda, Omar Batal, Michael Mathier, John Gorcsan

What Is New in Device Technology

Clinical Characteristics and Outcomes of CRT-P Versus CRT-D Recipients in Patients 80 Years and Older

Presented by: Muhammad Bilal Munir, Andrew Althouse, Shasank Rijal, Maulin B. Shah, Hussein Abu Daya, Evan Adelstein, Samir Saba

Monday, April 4

Beyond the Usual Suspects: The Atypical Cardiomyopathies

Galectin-3 Levels and Outcomes in Peripartum Cardiomyopathy: Results From the Multicenter IPAC Investigation

Presented by: Kate Elizabeth Groh, Rami Alharethi, Gregory Ewald, Michael Givertz, G. Michael Felker, Jessica Pisarcik, Karen Hanley-Yanez, Indrani Halder, Charles McTiernan, Dennis McNamara

Soluble IL2 Receptor and Survival in Recent Onset Cardiomyopathy Results of IMAC2

Presented by: Dennis McNamara, Leslie Cooper, Richard Sheppard, Jeffrey Alexis, Daniel Pauly, Karen Hanley-Yanez, Indrani Halder, Charles McTiernan

Cardiac Molecular Imaging

Echo Based Molecular Imaging Approaches

Presented by: Flordeliza S. Villanueva

Future of Cardiovascular Imaging: A Report From the ACC Think Tank

The Cardiovascular Imager of the Future

Presented by: Prem Soman

Late-Breaking Clinical Trials

The Final Results of the IxCell-DCM Trial: Transendocardial Injection of Ixmyelocel-T in Patients with Ischemic Dilated Cardiomyopathy

Timothy D. Henry, Arshed A. Quyyumi, Gary L. Schaer, David R. Anderson, Catalin Toma, Cara East, David A. Recker, Ann Remmers, James Goodrich, Amit Patel

Managing Cardiogenic Shock – Drugs to ECMO

Determining Candidacy for DT VAD or Transplant in the Setting of Cardiogenic Shock

Presented by: Jeffrey Teuteberg

Nuclear Cardiology: Beyond Perfusion Imaging

Feasibility and Value of Gated Blood Pool SPECT (GBPS) Assessment of RV Function in Patients Undergoing LVAD Implantation

Presented by: Christopher B. Link, Aditi Nayak, Luigi Lagazzi, Andrew Althouse, Jeffrey Teuteberg, Marc Simon, Robert Kormos, Prem Soman

Intra-Individual Comparison of Left Ventricular Ejection Fraction Volumes Derived from Solid State and Anger SPECT Imaging

Presented by: Christopher B. Link, Aditi Nayak, Luigi Lagazzi, Andrew Althouse, Jeffrey Teuteberg, Marc Simon, Robert Kormos, Prem Soman

Treatment of Patients with Stage D Heart Failure and Shock

Case Presentation – LVAD selection

Presented by: Jeffrey Teuteberg

For more information, visit the event website.